# Context Understanding Guide

> This guide is loaded and prepended to every Gemini gate prompt and every
> machine-learning context check the plugin performs. It teaches the AI
> layer how to analyze meaning, not isolated words, before deciding
> whether a phrase is safe or risky on a US research-use-only (RUO)
> peptide / research-chemical site.

---

## 1. Definition of Context

**Context** is the full meaning of a sentence or paragraph derived from the
words *around* the phrase in question — the qualifiers, the negations, the
subject of the sentence, the surrounding clauses, and the page the phrase
appears on. Looking at words in isolation will produce false positives AND
false negatives.

The single sharpest illustration:

> **"Not for human consumption"** is **SAFE** — it is a regulatory
> disclaimer telling the buyer this is NOT a food or drug.
>
> **"For human consumption"** is **DANGEROUS** — it is a drug-marketing
> claim that an RUO product is not allowed to make.

The literal substring `"human consumption"` appears in BOTH. A keyword
match would treat them identically. Context tells them apart.

### Core context principles

1. **Negation reverses meaning.** Any "not", "never", "no", "without",
   "we do not", "the product is not", or "this site is not" in front of a
   risk pattern flips that pattern from dangerous → safe.
2. **Subject-position matters.** "Customers report 12 lbs lost" is a
   testimonial claim (dangerous). "We do not display customer
   weight-loss claims" is a policy statement (safe).
3. **Defensive frames are not violations.** An Acceptable Use Policy
   that *lists* what buyers may NOT do is safe even when it literally
   contains the forbidden actions. A "we are not a pharmacy" disclaimer
   is safe even though it literally contains the word "pharmacy".
4. **Quotation flips meaning.** "Customers ask 'is this Ozempic?' — no,
   this is a research reference standard" — quoting a brand name inside
   a clarifying disclaimer is safe.
5. **Page type matters.** The same sentence on an internal compliance
   SOP page is not the same as on a public product page.
6. **Intent over wording.** A paraphrase that delivers the same
   drug-marketing meaning is just as risky as the literal phrase.
   Swapping "Wegovy" for "semaglutide" inside an equivalence frame
   ("same active ingredient as ___") does NOT make the passage compliant
   — the *frame* is the violation, not the brand token.

### Key context examples

| Phrase | Verdict | Why |
|---|---|---|
| "Not for human consumption" | SAFE | Negated disclaimer |
| "For human consumption" | DANGEROUS | Drug-use claim |
| "Customers report 12 lbs lost in 8 weeks" | DANGEROUS | Weight-loss outcome claim with human subject |
| "We do not publish customer outcome claims" | SAFE | Defensive policy statement |
| "Research use only" | SAFE | Explicit regulatory disclaimer |
| "Take 0.25mg subcutaneously once weekly" | DANGEROUS | Dosing + route + frequency |
| "Storage: lyophilized vial, store at -20°C" | SAFE | Storage instruction, not dosing |
| "Same active ingredient as Wegovy" | DANGEROUS | Brand-equivalence claim |
| "Semaglutide reference standard, lot ###" | SAFE | Identity + lot, no comparison frame |
| "Resale to compounding pharmacies is not permitted" | SAFE | AUP enumeration of prohibited use |
| "We compound this for telehealth providers" | DANGEROUS | Active claim of operating as a compounder |

---

## 2. Block List — high-risk meanings & implications

> Flag the **meaning**, not just the literal substring. Each item below is
> a family of phrasings that delivers the same dangerous intent. Match
> paraphrases, synonyms, and indirect implications — not just keywords.

### 2.1 Body-benefit / outcome claims

Any wording that implies a beneficial effect on a human body is
dangerous, regardless of phrasing.

**Weight / body composition**
- "lose weight", "weight loss", "shed pounds", "drop weight"
- "lose X pounds in Y weeks", "down X lbs", "12 lbs lost"
- "melt fat", "burn fat", "fat loss", "fat-burning"
- "slimmer figure", "smaller waistline", "drop a dress size"
- "leaner physique", "reduced body fat", "trim down", "get cut"
- "weight management", "weight reduction", "achieve your goal weight"
- "before and after photos", "transformation pictures"
- "scale victory", "scale moves", "see results on the scale"

**Muscle / strength**
- "muscle growth", "muscle gains", "lean mass", "build muscle"
- "hypertrophy", "anabolic effect", "anabolism"
- "bulking cycle", "cutting cycle", "recomp"
- "strength gains", "PRs", "lift heavier"
- "recovery time", "post-workout recovery", "reduced soreness"
- "performance enhancement"

**Anti-aging / skin / hair**
- "anti-aging", "age reversal", "look younger", "youthful"
- "wrinkle reduction", "smoother skin", "skin elasticity"
- "collagen production", "boost collagen"
- "hair growth", "thicker hair", "regrow lost hair", "scalp health"
- "fountain of youth", "turn back the clock"
- "longevity", "live longer", "extend lifespan"

**Appetite / metabolism / glucose**
- "appetite control", "suppress appetite", "reduce hunger"
- "feel full faster", "increased satiety", "control cravings"
- "blood sugar control", "lower glucose", "stable blood sugar"
- "insulin sensitivity", "diabetic control", "lower A1C"
- "speed up metabolism", "boost metabolism", "metabolic health"

**Energy / cognition / sleep**
- "more energy", "increased energy", "energy levels", "vitality"
- "fatigue relief", "stamina", "endurance"
- "mental clarity", "cognitive boost", "improved focus", "sharper mind"
- "memory enhancement", "brain fog lifted"
- "better sleep", "deeper sleep", "sleep quality", "improved REM"
- "wake up refreshed", "natural sleep aid"
- "stress relief", "anxiety reduction", "mood lift", "feel happier"

**Sexual / reproductive**
- "libido boost", "increased libido", "sexual desire"
- "improved performance", "stamina in bed"
- "erectile function", "ED relief", "arousal"
- "fertility support", "reproductive health"

**Cardiovascular / inflammation**
- "lower blood pressure", "heart health", "cardiovascular support"
- "reduce cholesterol", "improve lipid profile"
- "reduce inflammation", "anti-inflammatory effect"

**Hormonal**
- "boost testosterone", "raise T levels", "increased testosterone"
- "estrogen balance", "regulate hormones"
- "growth hormone release", "HGH increase", "elevate GH"

**Tissue repair / wound healing**
- "wound healing", "tissue repair", "faster healing"
- "joint repair", "cartilage regeneration", "tendon recovery"
- "injury recovery", "post-injury rehab"

### 2.2 Dosing / administration instructions

Any specific instruction on how a human should take, inject, or use
the product is dangerous regardless of phrasing.

**Dose values**
- "take X mg", "X mg daily", "X mcg per day", "X IU per week"
- "1-2 capsules", "one tablet twice daily", "serving size: X"
- "recommended dose", "recommended use", "suggested dose"
- "loading dose", "starting dose", "maintenance dose", "max dose"
- "titrate up", "titration schedule", "ramp up dose"
- "split dose", "divided dose", "morning dose, evening dose"

**Route**
- "inject", "injection", "self-inject", "intramuscular", "IM"
- "subcutaneous", "subq", "subcutaneously", "into the fat layer"
- "intravenous", "IV", "into the vein"
- "oral", "swallow", "place under the tongue", "sublingual"
- "nasal spray", "intranasal"
- "rotate injection sites"

**Reconstitution / preparation**
- "reconstitute with bacteriostatic water", "mix with BAC water"
- "draw X ml into the syringe", "pull X units"
- "swirl, do not shake", "let dissolve"
- "store in refrigerator after mixing"

**Timing / cycling**
- "once weekly", "twice weekly", "every other day", "EOD"
- "morning dose", "evening dose", "pre-bed", "with breakfast"
- "8 weeks on, 4 weeks off", "cycle length", "PCT"
- "before workout", "post-workout", "fasted"

### 2.3 Brand-equivalence / drug-comparison claims

Comparing an RUO product to any FDA-approved drug or branded medication
is dangerous, including indirect/paraphrased comparisons.

**Brand tokens (any of these in claim context)**
- GLP-1 / weight: Ozempic, Wegovy, Mounjaro, Zepbound, Saxenda,
  Rybelsus, Trulicity, Victoza, Byetta, Bydureon, Adlyxin
- Insulin: Lantus, Humalog, Novolog, Toujeo, Tresiba, Lyumjev
- Other: Cialis, Viagra, Adderall, Ritalin, Xanax

**Equivalence frames (the frame is the violation, even without a brand)**
- "same active ingredient as ___"
- "equivalent to ___", "alternative to ___", "comparable to ___"
- "compares to ___", "similar to ___", "works like ___"
- "as effective as ___", "as good as ___", "matches ___"
- "knock-off", "knockoff", "generic version of ___"
- "compound version of ___", "research-grade version of ___"
- "identical to ___", "same molecule as ___", "same compound as ___"
- "save money vs ___", "no prescription needed for ___"
- "Wegovy/Ozempic without the prescription"

### 2.4 Human-use framing

Any wording that frames the product as intended for a human user is
dangerous, including indirect framing.

- "patients", "patient outcomes", "for the patient"
- "consumers", "customers" (when used as the human recipient of the effect)
- "users", "end users" (in a human-receives-effect context)
- "for personal use", "ready to use", "single-use vial"
- "your daily dose", "what to expect when you take this"
- "before you start", "your first cycle", "after your first injection"
- "consult your doctor", "ask your physician"
- "side effects", "adverse reactions" (when describing experience)

### 2.5 Testimonial / endorsement / before-and-after

A first-person or third-person account of a human using the product is
dangerous, even when phrased as a "review" or "research log".

- "I lost X pounds in Y weeks"
- "after 4 weeks I felt ___"
- "real customers", "real results", "verified buyers"
- "before-and-after photos", "before/after pictures", "transformation pics"
- "customer stories", "success stories", "user testimonials"
- "review from a happy customer", "5-star review of my results"
- "my research subject (me, lol)", "the human test subject (myself)"
- "cycle log", "gains report", "results log"

### 2.6 Disease / therapeutic claims

Any wording that implies the product treats, cures, prevents, or
diagnoses a disease/condition is dangerous.

- "treats ___", "cures ___", "prevents ___", "diagnoses ___"
- "for the treatment of ___", "for relief of ___"
- "reduces symptoms of ___", "manages ___"
- "remedy for ___", "solution for ___"
- "type 2 diabetes", "obesity", "metabolic syndrome", "PCOS"
- "depression", "anxiety", "chronic fatigue", "insomnia"
- "erectile dysfunction", "low testosterone", "menopause"
- "Alzheimer's", "Parkinson's", "arthritis"
- "long COVID", "post-viral syndrome"

### 2.7 Unsupported credential / facility claims

Claims that the vendor holds a credential it does not actually hold
are dangerous.

- "FDA-approved facility", "FDA-registered manufacturer"
- "cGMP-certified", "GMP-certified" (without specific evidence)
- "ISO 17025", "ISO 13485" (without specific scope evidence)
- "AAALAC-accredited" (without evidence)
- "LegitScript-certified", "LegitScript-approved"
- "503A pharmacy", "503B compounder", "outsourcing facility"
- "licensed prescriber", "licensed pharmacy"
- "our clinic", "our medical staff", "our physicians"

### 2.8 Payment / underwriting workaround language

Wording that suggests circumventing card-network or processor rules is
dangerous and triggers immediate underwriting review.

- "crypto only", "Bitcoin only", "no credit cards"
- "backup processor", "secondary processor", "split transaction"
- "discreet billing", "discreet descriptor", "billing as ___"
- "manual invoice", "wire transfer only"
- "wallet address", "send to this BTC address"
- "no chargebacks accepted", "all sales final, no refunds ever"

### 2.9 Compounded-equivalent / pharmacy-equivalence implications

Wording that suggests the product is or substitutes for a compounded
prescription preparation.

- "compounded version", "research-grade compound"
- "for compounding pharmacies", "supplied to compounders"
- "telehealth-grade", "clinic-grade"
- "503A equivalent", "503B equivalent"

### 2.10 Marketing-claim pressure / scarcity tactics on health products

- "only X bottles left", "selling out fast", "limited supply this week"
- "ends today", "24 hour flash sale on ___"
- "exclusive offer for first-time researchers"
- (When paired with any body-effect or dose context: dangerous.)

---

## 3. Allow List — safe research disclaimers

> These phrasings, when clearly present in the immediate context of a
> potentially-risky phrase, **override** the Block List. The combined
> meaning becomes "this is a research material, not a drug claim."
> The disclaimer must be in the same paragraph or visually attached to
> the matched text to count as an override — a buried site-footer
> disclaimer 800 words away from a dosing instruction does not.

### 3.1 Core RUO disclaimers (canonical forms)

- "research use only", "for research use only", "RUO", "(RUO)"
- "for research purposes only", "for research purposes"
- "for laboratory use only", "for laboratory research only"
- "for laboratory research"
- "for scientific research only", "for scientific research purposes"
- "for academic research only", "for academic and scientific research"
- "not intended for human use", "not for human use"
- "not intended for human consumption", "not for human consumption"
- "not for human or animal consumption", "not for human or animal use"
- "in vitro studies", "in vitro use only", "in-vitro use only"
- "for in-vitro evaluation"

### 3.2 Extended research-context disclaimers

- "non-clinical research only", "preclinical research only"
- "for qualified researcher use only", "qualified researchers only"
- "for qualified laboratory personnel only"
- "ships to verified researchers only", "verified-researcher accounts only"
- "intended only for in-vitro research", "exclusively for in-vitro research"
- "for use in a controlled laboratory environment"
- "research chemical, not for human consumption"
- "research compound, not approved for human use"
- "reference standard", "analytical reference standard"
- "reference material for analytical purposes"
- "study compound", "investigational research material"
- "synthesis precursor", "intermediate for research synthesis"
- "for assay validation", "for assay development"
- "for biochemical research", "for biomedical research"
- "for analytical purposes", "for HPLC reference"
- "method development", "method validation reference"
- "calibration standard", "analytical standard"
- "for use as a laboratory reagent"

### 3.3 Negative / disclaimer-frame statements

These statements say what the product is NOT — and that negation flips
nearby risk patterns from dangerous to safe.

- "not approved by the FDA"
- "not FDA approved", "not FDA-approved"
- "not approved by the U.S. Food and Drug Administration"
- "not approved for human consumption"
- "not approved for clinical use"
- "not approved for therapeutic use"
- "not approved for veterinary use"
- "not a drug", "not a medicine", "not a medication"
- "not a dietary supplement", "not a food"
- "not a cosmetic", "not a medical device"
- "not a prescription product", "not a prescription drug"
- "not intended to diagnose"
- "not intended to treat"
- "not intended to cure"
- "not intended to prevent"
- "not intended to mitigate"
- "no medical claims are made"
- "the statements on this page have not been evaluated by the FDA"
- "this product makes no health claims"
- "the seller makes no representations about efficacy"

### 3.4 Vendor-identity disclaimers (limit-of-role)

These statements clarify the vendor is not operating as a pharmacy /
clinic / prescriber and flip nearby pharmacy/clinic-context patterns
from dangerous to safe.

- "we are not a pharmacy", "this is not a pharmacy"
- "we are not a clinic", "this is not a clinic"
- "we are not a healthcare provider"
- "we are not a licensed prescriber"
- "we are not a 503A pharmacy", "we are not a 503B outsourcing facility"
- "we do not dispense medications", "we do not compound"
- "we do not provide medical advice"
- "we do not offer telehealth services", "we do not provide telemedicine"
- "we do not have a pharmacist on staff", "we do not employ prescribers"
- "no medical consultation is provided", "no clinical care is provided"
- "the seller is a research-chemical vendor", "we are a research-use-only vendor"
- "vendor only", "reseller only", "distributor only", "supplier only"
- "research-chemical vendor", "research-use vendor"

### 3.5 Buyer-acknowledgment / qualified-researcher framing

These statements indicate the buyer has been screened as a researcher
and shift the product's apparent audience away from consumers.

- "you certify you are a qualified researcher"
- "buyer affirms research use only"
- "buyer acknowledges this is for laboratory research"
- "buyer attests to ORCID / institutional affiliation"
- "purchase requires verified-researcher status"
- "you must hold an institutional research role to order"

### 3.6 Acceptable-use-policy enumeration frames

Inside an Acceptable Use Policy / Terms of Service / Compliance page,
text that LISTS prohibited uses is safe even when those listed uses
contain risk terms. Recognize the frame:

- "you may not use this site to ___"
- "the following uses are prohibited: ___"
- "resale to ___ is not permitted"
- "use of this product for ___ is forbidden"
- "we do not permit the use of this product for ___"
- "this policy bans the following: ___"
- "the buyer agrees not to ___"
- "the buyer shall not ___"
- "this product is not to be used for ___"

### 3.7 Quality / chain-of-custody framing (research catalog voice)

Wording that describes the product as a research catalog entry —
identity, lot, purity, storage, COA — is safe and does NOT need an
explicit RUO disclaimer to be recognized as safe.

- "lyophilized vial", "lyophilized powder"
- "lot number ___", "batch ID ___"
- "purity 99%", "purity ≥ 99%", "≥99% purity by HPLC"
- "store at -20°C", "store frozen", "store at room temperature"
- "Certificate of Analysis available on request"
- "COA available", "COA on file", "third-party COA"
- "molecular weight: ___", "MW: ___ Da"
- "CAS number ___"
- "sequence: ___" (peptide sequence in scientific format)
- "characterization by mass spec / HPLC"

---

## 4. How to use this guide before every scan

When the AI layer (Gemini gate, ML context model, rewrite endpoint)
analyzes a candidate finding:

1. **Read the full sentence** containing the matched phrase, not just
   the matched substring.
2. **Walk outward** to the surrounding paragraph and the page type
   (product, AUP, terms, FAQ, internal SOP).
3. **Apply the Allow List first.** If any disclaimer from Section 3 is
   present in the immediate context, treat the matched phrase as safe.
4. **Apply the Block List second.** If no allow-list override applies,
   match the *meaning* of the phrase against Section 2 — including
   paraphrases, synonyms, and indirect implications.
5. **Report the decision** with one sentence of reasoning so the
   merchant can review and the system can learn (e.g., "Confirmed:
   weight-loss outcome claim with no RUO disclaimer in the same
   paragraph", or "Dropped: 'human consumption' is preceded by 'not' —
   this is a disclaimer, not a claim").

When in doubt, KEEP the candidate as a finding (return `confirmed` or
`softened`). Only return `false_positive` when the surrounding context
CLEARLY defangs the trigger via the Allow List.
